CONTRACTOR Sr. Research Associate/Associate Scientist, Analytical Development

**Please note that this is a full time (40 hour/week), onsite, contractor position.

Position Summary

We are seeking an experienced and motivated Associate to join the Analytical Development team. This position works with the PTCC team to develop and/or improve cell-based assays for cell product characterization and release. The Analytical Development Associate participates in laboratory activities to support process development, evaluate and develop new assay methods, and perform product characterization for CAR-T cell products. He/she is also involved in assay optimization and standardization and assay transfer to internal or external QC labs. Under reasonable supervision, the role includes performing assay development experiments, carefully documenting methods and materials, writing SOPs/reports, and communicating findings. The ideal candidate has a proven track record of innovation, demonstrated skill set and knowledge in process and analytical development, and is excited to take on new challenges in a fast-paced and dynamic environment.

Responsibilities

These may include but are not limited to:

• Develops analytical test method procedures in accordance with relevant guidelines from ICH, USP, EP for cell therapy product GMP release testing and characterization.
• Supports analytical routine testing, qualification, and validation.
• Evaluates reagents and supplies to meet QC standards
• Co-authors test methods (SOPs), technical reports, and analytical sampling plans
• Documents laboratory procedures and experiments with great attention to detail in laboratory notebooks
• Performs assays for process assessment and product characterization
• Participates in assay transfers to QC and provides lifecycle support
• Evaluates alternative technologies to create robust and reproducible analytical methods
• Sets up, monitors, samples, and analyzes cell culture processes
• Works with R&D teams to gain deeper understanding of the analytical methods for characterization of product critical quality attributes

Requirements, Knowledge, Skills and Abilities

• BS or MS degree in a relevant scientific discipline with two plus years of relevant experience in a biotech
• environment (an equivalent combination of education and experience may be considered)
• Experience in human T cell biology with demonstrated proficiency in a broad range of cellular immunology techniques, including flow cytometry.
• Experiences with aseptic cell culture (human primary cells and cell lines) and bio-assay development and/or testing
• Ability to follow laboratory procedures with attention to detail, and successfully execute experiments at the bench
• Demonstrated ability to maintain detailed lab execution records and perform data analysis
• Excellent communication skills, data presentation and interpersonal skills
• Basic computer skills in Excel, PowerPoint, and word processing
• Attention to detail, initiative, and strong organizational skills
• Demonstrated ability to work in a fast-paced small company environment with reasonable direction and able to adjust workload based upon changing priorities.

Preferred Qualifications

• Minimum of two plus years of relevant industry experience
• Foundation in experimental documentation, basic statistical analysis, and data presentation
• Exposure in vitro T cell functional assays (potency, cytotoxicity, ELISA, proliferation, Luminex)
• Basic skills in molecular techniques including qPCR or ddPCR and electrophoresis.
• Experience with drafting SOP and forms
• Develops assays for cell product release and characterization by designing and executing studies via design of experiment (DoE)

Senior Research Associate Pay Rate: $28.65/hour to $53.17/hour

Associate Scientist Pay Rate: $59,600 to $110,600 annually

The final pay offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the job, type, and length of experience with the industry, education, geographic location, etc.

Who We Are:

Poseida Therapeutics was acquired by Roche in early 2025 and is now part of the Roche Group. Poseida is a clinical-stage biopharmaceutical company advancing differentiated allogeneic cell therapies and genetic medicines with the capacity to cure. The Company's approach is based on its proprietary genetic editing platforms, including its non-viral DNA Delivery System, Cas-CLOVER Site-Specific Gene Editing System, Booster Molecule and nanoparticle gene delivery technologies, as well as in-house GMP cell therapy manufacturing.

Our people are as important as our cutting-edge technology. That's why we invest in offering excellent career development opportunities to our employees, as well as highly competitive compensation and comprehensive benefits. We are committed to giving employees the resources they need to thrive, personally and professionally.

Within the Roche organization, a healthier future drives us to innovate. Together, more than 100'000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let's build a healthier future, together.