Postdoctoral Associate
 Duke Clinical Research Institute | |
 United States, North Carolina, Durham | |
 Jul 14, 2026 | |
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School of Medicine Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations. Be You. Postdoctoral Associate - Regenerative CAR T Therapy for Duchenne Muscular Dystrophy This Postdoctoral Associate will serve on a project focused on developing regenerative CAR T-based therapeutic strategies for Duchenne muscular dystrophy (DMD), funded by NIH R21 project (1R21AR087645-01). The project aims to target pathogenic inflammatory and fibrotic stromal cell populations that impair muscle regeneration in DMD. The Postdoctoral Associate will design and perform experiments to validate therapeutic targets, develop and test CAR T-cell strategies, and evaluate treatment effects in DMD mouse models. Key responsibilities will include flow cytometry, tissue histology, molecular and cellular assays, analysis of muscle degeneration and regeneration, and integration of single-cell/genomic data to define therapeutic mechanisms. Min Degree Requirements:The position requires expertise and PhD in molecular biology, cell biology, mouse models, and quantitative data analysis. Other Credential/Experiential Requirements:Experience in muscle biology, immunology, CAR T-cell engineering, fibrosis, or single-cell genomics is highly desirable This position is
Be Bold. The Postdoctoral Associate will also contribute to manuscripts, grant materials, presentations, and collaborative project development. Duke is an Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex (including pregnancy and pregnancy related conditions), sexual orientation or military status. Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas-an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values. Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department. | |